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One recent study from Yale University found that vanillin — an extract of the vanilla bean — transforms into chemicals referred to as acetals when aerosolized. Those chemicals, the researchers said, may be particularly irritating to the lungs and cause damage when inhaled. Studies have shown that breathing in aerosolized propylene glycol might contribute to bronchial asthma. And a 2012 case report concerned a girl who developed a condition known as exogenous lipoid pneumonia after vaping for about six months.

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